Dani Pedrosa transformed fantastic form from practice sessions to dominant race victory, never letting his rivals to even get close. This was the first time for Spanish rider to take back-to-back victories in MotoGP class, but according to his form, certainly not the last. Jorge Lorenzo gathered more valuable championship points by taking second place, never being able to challenge Pedrosa for victory, but also never being challenged for second position. Valentino Rossi returned to podium for his home race, managing to defend last podium step from charging Andrea Dovizioso.

Dovizioso was strong through the race, constantly riding behind Rossi in 4th place, but eventually not being able to make attack and get to podium. Casey Stoner, who was third in opening laps of the race, lost his speed as race progressed and finished in dissappointing 5th place. Ben Spies recovered from start which saw him ending in 10th place in lap 1, finishing race in 6th place. Colin Edwards finished race in 7th place, right behind his team-mate.

Alvaro Bautista brought 8th place to Suzuki in hard fought mid-field battle, while his team-mate Capirossi was taken out from the track in lap 1 by Nicky Hayden. Hector Barbera took respectable 9th place after fighting with Marco Melandri, who completed top 10 finishers in Misano.

Misano - MotoGP race results